Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine.

Gastrointestinal (GI) dysfunction often occurs in critically ill but can be ignored as a result of lack of standardized diagnostic and therapeutic approaches. We aim to develop a research agenda for GI dysfunction for future research. We systematically the current knowledge on various subtopics of a particular viewpoint GI dysfunction, highlighted the remaining areas of uncertainty and suggested agenda of reviews scoping and systematic study of the future of studies.

This do the following steps in succession: (1) identify clinically important subtopics in the field GI function which ensures further research; (2) systematically reviewed the literature for each subtopic using PubMed, CENTRAL and the Cochrane Database of Systematic Reviews; (3) Evidence of summarizing for each subtopic; (4) identify areas of uncertainty; (5) formulates and flute studies that discuss the proposal this subtopics; and (6) a proposal to prioritize study through voting consecutive major rounds.Five themes identified: (1) monitoring, (2) the relationship between GI function and results, (3) GI function and nutrition, (4) management of GI dysfunction and (5 ) pathophysiological mechanisms.

Search in 17 subtopics conducted and evidence summarized. Some areas of uncertainty are identified, six of them require the consensus process. research proposals in the first rank among the top ten include: prevention and management of diarrhea; eating intolerance management above and below, including indications for a post-pyloric and opioid antagonist; Acute gastrointestinal injury levels as a bedside tool; intra-abdominal hypertension role in the development and monitoring of GI dysfunction and the development of non-occlusive mesenteric ischemia; and the effects of proton pump inhibitors on the microbiome in illness.

Current evidence critical of GI dysfunction rare, partly because of the lack of a precise definition. The use of a core set of monitoring and results needed to improve the consistency of future studies. We proposed several areas for the consensus process and research projects frontline.

Indirect Bilirubin Positive Serum Samples
MBS173613-5Samples	MyBiosource	5Samples	EUR 995

Indirect Bilirubin Positive Serum Samples
MBS173613-5x5Samples	MyBiosource	5x5Samples	EUR 4270

Bilirubin Antigen (Indirect and Unconjugated)
VAng-Cr3867-25mg	Creative Biolabs	25 mg	EUR 604.8
Description: Bilirubin Antigen (Indirect and Unconjugated), Host/Source: Porcine Gall Bladder. The purity is> 95% pure by SDS-PAGE.

Bilirubin - Indirect and Unconjugated, Porcine
MBS173237-100mg	MyBiosource	100mg	EUR 315

Bilirubin - Indirect and Unconjugated, Porcine
MBS173237-1g	MyBiosource	1g	EUR 415

Bilirubin - Indirect and Unconjugated, Porcine
MBS173237-25mg	MyBiosource	25mg	EUR 205

Bilirubin - Indirect and Unconjugated, Porcine
MBS173237-5x1g	MyBiosource	5x1g	EUR 1360

Recombinant Bactrocera dorsalis Actin, indirect flight muscle
MBS1201745-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1250

Recombinant Bactrocera dorsalis Actin, indirect flight muscle
MBS1201745-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 915

Recombinant Bactrocera dorsalis Actin, indirect flight muscle
MBS1201745-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 1040

Recombinant Bactrocera dorsalis Actin, indirect flight muscle
MBS1201745-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 1100

Recombinant Bactrocera dorsalis Actin, indirect flight muscle
MBS1201745-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1180

Recombinant Drosophila simulans Actin, indirect flight muscle (Act88F)
MBS1244631-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1250

Recombinant Drosophila simulans Actin, indirect flight muscle (Act88F)
MBS1244631-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 915

Recombinant Drosophila simulans Actin, indirect flight muscle (Act88F)
MBS1244631-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 1040

Recombinant Drosophila simulans Actin, indirect flight muscle (Act88F)
MBS1244631-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 1100

Recombinant Drosophila simulans Actin, indirect flight muscle (Act88F)
MBS1244631-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1180

Recombinant Drosophila melanogaster Actin, indirect flight muscle (Act88F)
MBS1008602-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1250

Recombinant Drosophila melanogaster Actin, indirect flight muscle (Act88F)
MBS1008602-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 915

Recombinant Drosophila melanogaster Actin, indirect flight muscle (Act88F)
MBS1008602-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 1040

Recombinant Drosophila melanogaster Actin, indirect flight muscle (Act88F)
MBS1008602-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 1100

Recombinant Drosophila melanogaster Actin, indirect flight muscle (Act88F)
MBS1008602-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1180

Human Urokinase (uPA) Chromogenic AssaySense Activity Assay Kit (Indirect Assay)
CU1001b	AssayPro	96 Well Plate	EUR 545

PCP Direct ELISA
GWB-BQK187	GenWay Biotech	96 Well Plate	Ask for price

Renin ELISA (Direct)
GWB-013014	GenWay Biotech	96 Tests	Ask for price

Cotinine Direct ELISA
GWB-BQK0DA	GenWay Biotech	96 well plate	Ask for price

Methadone Direct ELISA
GWB-BQK185	GenWay Biotech	96 Well Plate	Ask for price

Amphetamine ELISA (Direct)
GWB-BQK179	GenWay Biotech	96 Well Plate	Ask for price

Barbiturates ELISA (Direct)
GWB-BQK17F	GenWay Biotech	96 Well Plate	Ask for price

Methamphetamine Direct ELISA
GWB-BQK0F5	GenWay Biotech	96 well plate	Ask for price

Benzodiazepines ELISA (Direct)
GWB-BQK183	GenWay Biotech	96 Well Plate	Ask for price

Cyclic GMP (Direct) ELISA
MBS494508-5x96Tests	MyBiosource	5x96Tests	EUR 3410

Cyclic GMP (Direct) ELISA
MBS494508-96Tests	MyBiosource	96Tests	EUR 740

Morphine Specific ELISA (Direct)
GWB-BQK186	GenWay Biotech	96 Well Plate	Ask for price

Cocaine / Benzoylecgonine ELISA (Direct)
GWB-BQK11F	GenWay Biotech	96 Well Plate	Ask for price

Rat Direct Bilirubin,DBIL ELISA KIT
E2627Ra-1096T	Jiaxing Korain Biotech Ltd (BT Labs)	10*96T	EUR 4122

Rat Direct Bilirubin,DBIL ELISA KIT
E2627Ra-48wells	Jiaxing Korain Biotech Ltd (BT Labs)	48 wells	EUR 300

Rat Direct Bilirubin,DBIL ELISA KIT
E2627Ra-596T	Jiaxing Korain Biotech Ltd (BT Labs)	5*96T	EUR 2061

Rat Direct Bilirubin,DBIL ELISA KIT
E2627Ra-96wells	Jiaxing Korain Biotech Ltd (BT Labs)	96 wells	EUR 458

Rat Direct Bilirubin, DBIL ELISA Kit
MBS1607953-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3955

Rat Direct Bilirubin, DBIL ELISA Kit
MBS1607953-48StripWells	MyBiosource	48-Strip-Wells	EUR 305

Rat Direct Bilirubin, DBIL ELISA Kit
MBS1607953-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2005

Rat Direct Bilirubin, DBIL ELISA Kit
MBS1607953-96StripWells	MyBiosource	96-Strip-Wells	EUR 475

GWB-BQK0DA-96W - Cotinine Direct ELISA
GWB-BQK0DA-96W	Aviva Systems Biology	96Wells	EUR 359

Human Mumps IgG ELISA Kit (Direct EIA)
EK7073	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Mumps IgM ELISA Kit (Direct EIA)
EK7074	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Cyclic AMP Direct ELISA Kit (1 Plate)
K019-H1	Arbor Assays	1x96 well plate	EUR 431
Description: Cyclic AMP (cAMP) Direct ELISA / assay Kit

Cyclic AMP Direct ELISA Kit (5 Plate)
K019-H5	Arbor Assays	5x96 well plate	EUR 1723
Description: Cyclic AMP (cAMP) Direct ELISA / assay Kit

Cyclic GMP Direct ELISA Kit (1 Plate)
K020-H1	Arbor Assays	1x96 well plate	EUR 407

Cyclic GMP Direct ELISA Kit (5 Plate)
K020-H5	Arbor Assays	5x96 well plate	EUR 1593

Human Rubella IgG ELISA Kit (Direct EIA)
EK7082	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Rubella IgM ELISA Kit (Direct EIA)
EK7083	BosterBio	96wells/kit, with removable strips.	EUR 573.6

ANA IgG Screening ELISA Kit (Direct EIA)
EK7016	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Brucella IgG ELISA Kit (Direct EIA)
EK7021	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Brucella IgM ELISA Kit (Direct EIA)
EK7022	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Toxoplasma IgG ELISA Kit (Direct EIA)
EK7099	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Toxoplasma IgA ELISA Kit (Direct EIA)
EK7100	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Toxoplasma IgM ELISA Kit (Direct EIA)
EK7101	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Direct Red 80
TD0098-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Direct Red 80

Direct Red 80
TD0098-1g	TargetMol Chemicals	1g	Ask for price
Description: Direct Red 80

Direct Red 80
TD0098-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Direct Red 80

Direct Red 80
TD0098-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Direct Red 80

Direct Red 80
TD0098-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Direct Red 80

Direct Red 80
MBS5786703-1g	MyBiosource	1g	EUR 145

Direct Red 80
MBS5786703-5mg	MyBiosource	5(mg	EUR 145

Direct Red 80
MBS5786703-5x1g	MyBiosource	5x1g	EUR 500

Direct Red 80
MBS5786703-5x5mg	MyBiosource	5x5mg	EUR 500

Human HSV-1 IgG ELISA Kit (Direct EIA)
EK7058	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human HSV-1 IgM ELISA Kit (Direct EIA)
EK7059	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human HSV-2 IgG ELISA Kit (Direct EIA)
EK7060	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human HSV-2 IgM ELISA Kit (Direct EIA)
EK7061	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Cardiolipin IgG ELISA Kit (Direct EIA)
EK7024	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Cardiolipin IgA ELISA Kit (Direct EIA)
EK7025	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Cardiolipin IgM ELISA Kit (Direct EIA)
EK7026	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Direct Blue 71
D494318	Toronto Research Chemicals	2.5g	EUR 68
Description: 4399-55-7

Direct WGA Kit
PCR-382L	Jena Bioscience GmbH	100reactions x 20 µl	EUR 566.6

Direct WGA Kit
PCR-382S	Jena Bioscience GmbH	20reactions x 20 µl	EUR 141.8

Direct Blue 1
T2194-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Direct Blue 1

Direct Blue 1
T2194-1g	TargetMol Chemicals	1g	Ask for price
Description: Direct Blue 1

Direct Blue 1
T2194-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Direct Blue 1

Direct Blue 1
T2194-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Direct Blue 1

Direct Blue 1
T2194-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Direct Blue 1

Direct Black 38
HY-D0256	MedChemExpress	100mg	EUR 129.6

Direct Green 6
T31526-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Direct Green 6

Direct Green 6
T31526-1g	TargetMol Chemicals	1g	Ask for price
Description: Direct Green 6

Direct Green 6
T31526-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Direct Green 6

Direct Green 6
T31526-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Direct Green 6

Direct Green 6
T31526-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Direct Green 6

Direct Black 38
T15135-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Direct Black 38

Direct Black 38
T15135-1g	TargetMol Chemicals	1g	Ask for price
Description: Direct Black 38

Direct Black 38
T15135-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Direct Black 38

Direct Black 38
T15135-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Direct Black 38

Direct Black 38
T15135-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Direct Black 38

Direct Green 6
MBS5781130-INQUIRE	MyBiosource	INQUIRE	Ask for price

Direct Black 38
MBS5754793-100mg	MyBiosource	100mg	EUR 145

Direct Black 38
MBS5754793-5x100mg	MyBiosource	5x100mg	EUR 500

Direct Violet 1
596135	MedKoo Biosciences	25.0g	EUR 230

Direct Yellow 26
464247	MedKoo Biosciences	10.0mg	Ask for price

Direct Yellow 11
D494828	Toronto Research Chemicals	10g	EUR 800
Description: 1325-37-7

Direct Violet 1
T20033-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Direct Violet 1

Direct Violet 1
T20033-1g	TargetMol Chemicals	1g	Ask for price
Description: Direct Violet 1

Direct Violet 1
T20033-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Direct Violet 1

Direct Violet 1
T20033-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Direct Violet 1

Direct Violet 1
T20033-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Direct Violet 1

Direct Violet 1
MBS5765613-100mg	MyBiosource	100mg	EUR 245

Direct Violet 1
MBS5765613-10mg	MyBiosource	10mg	EUR 145

Direct Violet 1
MBS5765613-200mg	MyBiosource	200mg	EUR 315

Direct Violet 1
MBS5765613-25mg	MyBiosource	25mg	EUR 165

Direct Violet 1
MBS5765613-50mg	MyBiosource	50mg	EUR 195

Direct Cyclic GMP (cGMP) ELISA Kit (1 Plate)
K065-H1	Arbor Assays	1x96 well plate	EUR 444
Description: Direct Cyclic GMP (cGMP) ELISA / assay Kit

Direct Cyclic GMP (cGMP) ELISA Kit (5 Plate)
K065-H5	Arbor Assays	5x96 well plate	EUR 1775
Description: Direct Cyclic GMP (cGMP) ELISA / assay Kit

OKAU00110-1PLATE - Cyclic AMP Direct ELISA Kit
OKAU00110-1PLATE	Aviva Systems Biology	1plate	EUR 400

OKAU00110-5PLATE - Cyclic AMP Direct ELISA Kit
OKAU00110-5PLATE	Aviva Systems Biology	5plate	EUR 1469

OKAU00111-1PLATE - Cyclic GMP Direct ELISA Kit
OKAU00111-1PLATE	Aviva Systems Biology	1plate	EUR 400

OKAU00111-5PLATE - Cyclic GMP Direct ELISA Kit
OKAU00111-5PLATE	Aviva Systems Biology	5plate	EUR 1569

Human Dengue Virus IgG ELISA Kit (Direct EIA)
EK7045	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Dengue Virus IgM ELISA Kit (Direct EIA)
EK7046	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Probe Direct SuperMix
abx461057-1096tests	Abbexa	10 × 96 tests	Ask for price

Probe Direct SuperMix
abx461057-596tests	Abbexa	5 × 96 tests	EUR 2800

Probe Direct SuperMix
abx461057-96tests	Abbexa	96 tests	EUR 812.5

Human Measles (Rubeola) IgG ELISA Kit (Direct EIA)
EK7075	BosterBio	96wells/kit, with removable strips.	EUR 573.6

Human Measles (Rubeola) IgM ELISA Kit (Direct EIA)
EK7076	BosterBio	96wells/kit, with removable strips.	EUR 573.6